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K11-linked Tri-Ubiquitin recombinant protein

K11-linked Tri-Ubiquitin

Product info
Concentration 2.5
Calculated MW 25.656 kDa (Band migrates faster on gels)
Additional Info
Assay&Purity Western Blot; ≥95%
Assay2&Purity2 N/A;
Format Liquid
Storage -80°C; 2.5 mg/ml in 20 mM Tris-HCl, pH 7.5, 0.15 M NaCl and 1 mM EDTA.
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Increasingly, researchers are focusing on the role poly-ubiquitin chains linked through K11. This post-translational modification has been linked to the ERAD cycle as a signal, similar to K48 linkage, for proteasomal degradation. More recently, K11 linkage appears to play an important role in cell cycle signaling, as it is associated with the anaphase promoting complex (APC) of ubiquitination machinery. These tri-ubiquitin chains are generated from the enzymatic linkage (UBE2S) of wild-type ubiquitin through lysine 11 and purified to >95% homogeneity by ion exchange chromatography.

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$ 255.00
Cat# PBV10655r
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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