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Human recombinant protein UBE2D3

Human recombinant UBE2D3

Product info
Primary Accession P61077
Calculated MW 28.707 kDa with a His6SUMO Tag
Additional Info
Gene ID 7323
Gene Symbol UBE2D3
Other Names Ubiquitin-conjugating enzyme E2 D3, Ubiquitin-protein ligase D3, Ubiquitin carrier protein D3, Ubiquitin-conjugating enzyme E2-17 kDa 3, UBC4/5, UBCH5C, MGC5416, MGC43926, UBE2D3.
Gene Source Human
Assay&Purity RP-HPLC; ≥95%
Assay2&Purity2 N/A;
Recombinant Yes
Format Liquid
Storage -80°C; 75 µL of a 40 µM solution (3 nmoles) in 25 mM Tris, pH 7.5, 150 mM NaCl, 10 mM DTT and 10% glycerol.
Citations (0)

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UBE2D3 (UbcH5b) is an E2 (ubiquitin conjugating enzyme) that is involved in the conjugation of ubiquitin to target substrates along with E1 and E3 enzymes. The UbcH5 family (including UbcH5a and UbcH5c, having 88% and 89% sequence identity with UbcH5b respectively) are the human homologues of the Saccharomyces cerevisiae UBC4/5 family (~79% sequence identity). Members of the UbcH5 family have been implicated in a number of inflammatory and cancer pathways including the ubiquitylation of p53 and IκBα with the help of different E3 ligases (Hdm2 and SCF complexes respectively).


Jensen J.P.,et al.J. Biol. Chem. 270:30408-30414(1995).
Chang H.-M.,et al.Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).

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$ 290.00
Cat# PBV10662r
(40 western blots)
Availability: 5-7days
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