Human recombinant protein UBE2R2 (Ubc3B)
Human recombinant UBE2R2 (Ubc3B)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q712K3 |
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Calculated MW | 27.166 kDa |
Gene ID | 54926 |
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Gene Symbol | UBE2R2 |
Other Names | Human recombinant UBE2R2 (Ubc3B), Cdc34b, Ubc3B, Ubiquitin-conjugating enzyme E2 R2Ubiquitin carrier protein R2, Ubiquitin-conjugating enzyme E2-CDC34B, Ubiquitin-protein ligase R2. |
Gene Source | Human |
Assay&Purity | RP-HPLC; ≥95% |
Assay2&Purity2 | N/A; |
Recombinant | Yes |
Format | Liquid |
Storage | -80°C; 75 µL of a 40 µM solution (3 nmoles) in TBS. |
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Provided below are standard protocols that you may find useful for product applications.
Background
UBE2R2 is a 238 amino acid (27.2 kDa) pre-protein from chromosome 9. After CK2-mediated UBE2R2 phosphorylation, it binds to the F-Box protein beta-TrCP, which is the subunit recognition subunit of an SCF E3 ligase. UBE2R2 may be involved in degradation of beta-catenin.
References
Semplici F.,et al.Oncogene 21:3978-3987(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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