|Calculated MW||30 to 38 kDa, homodimer, glycosylated.|
|Other Names||Osteogenic Protein 1, BMP-7|
|Source||Human 293 cell expressed|
|Results||50 to 250 ng/ml|
|Application Notes||Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.|
|Storage||-80°C; Lyophilized from a solution of 50 mM sodium acetate, pH 4.5, with 50 mM NaCl.|
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Provided below are standard protocols that you may find useful for product applications.
BMP7 belongs to the transforming growth factor-beta (TGFβ) superfamily. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Based on its expression early in embryogenesis, BMP-7 has a proposed role in early development. In addition, the fact that BMP-7 is closely related to BMP5 has led to speculation of possible bone inductive activity.
Oezkaynak E.,et al.EMBO J. 9:2085-2093(1990).
Celeste A.J.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:9843-9847(1990).
Deloukas P.,et al.Nature 414:865-871(2001).
Swencki-Underwood B.,et al.Protein Expr. Purif. 57:312-319(2008).
Yanagita M.,et al.Biochem. Biophys. Res. Commun. 316:490-500(2004).
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