|Calculated MW||17 kDa, monomer, non-glycosylated|
|Other Names||Prostatropin, HBGH-2, HBGF-2, FGF-2, FGF-b.|
|Source||Human cell expressed|
|Results||0.1 to 0.5 ng/ml|
|Application Notes||Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.|
|Storage||-80°C; Lyophilized from a PBS solution.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
FGF-basic is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described. The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors.
Abraham J.A.,et al.Cold Spring Harb. Symp. Quant. Biol. 51:657-668(1986).
Abraham J.A.,et al.EMBO J. 5:2523-2528(1986).
Prats H.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:1836-1840(1989).
Goshima N.,et al.Nat. Methods 5:1011-1017(2008).
Hillier L.W.,et al.Nature 434:724-731(2005).
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