|Calculated MW||24 to 30 kDa, monomer, glycosylated|
|Other Names||Fms-related tyrosine kinase 3 ligand, FLK2, STK1, CD135, Stem Cell Tyrosine Kinase 1, FLT3LG, Flt3.|
|Source||Human 293 cell expressed|
|Results||0.2 to 0.8 ng/ml|
|Application Notes||Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.|
|Storage||-80°C; Lyophilized from a PBS solution.|
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Provided below are standard protocols that you may find useful for product applications.
FLT3 ligand is a receptor for the Flt3 cytokine and has a tyrosine-protein kinase activity & a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand synergizes with other CSFs and interleukins to induce growth and differentiation. Human flt3-Ligand (flk2-ligand) stimulates the proliferation and colony formation of certain bone marrow precursor cells including CD34+ cells.
Small D.,et al.Proc. Natl. Acad. Sci. U.S.A. 91:459-463(1994).
Rosnet O.,et al.Blood 82:1110-1119(1993).
Dunham A.,et al.Nature 428:522-528(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Rosnet O.,et al.Genomics 9:380-385(1991).
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