|Calculated MW||21 to 25 kDa, monomer, glycosylated|
|Other Names||CSF-3, MGI-1G, GM-CSF beta, Pluripoietin, Filgrastim, Lenograstim, G-CSF, MGC45931, GCSF.|
|Source||Human 293 cell expressed|
|Results||0.02 to 0.08 ng/ml|
|Application Notes||Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.|
|Storage||-80°C; Lyophilized from a PBS solution.|
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Provided below are standard protocols that you may find useful for product applications.
GCSF is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Three transcript variants encoding three different isoforms have been found for the GCSF gene. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.
Nagata S.,et al.Nature 319:415-418(1986).
Nagata S.,et al.EMBO J. 5:575-581(1986).
Devlin J.J.,et al.J. Leukoc. Biol. 41:302-306(1987).
Jin P.,et al.Genomics 83:566-571(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
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