|Calculated MW||70 kDa, single chain, glycosylated|
|Other Names||Scatter Factor (SF), Hepatopoietin (HPTA), HGF, HGFB, F-TCF.|
|Source||Human 293 cell expressed|
|Results||10 to 50 ng/ml|
|Application Notes||Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.|
|Storage||-80°C; Lyophilized in solution of 10 mM Tris-HCl, pH 7.4, with 1 M NaCl.|
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Provided below are standard protocols that you may find useful for product applications.
Hepatocyte Growth Factor (HGF) is a multifunctional growth factor which regulates both cell growth and cell motility. It exerts a strong mitogenic effect on hepatocytes and primary epithelial cells. HGF synergizes with Interleukin-3 and GM-CSF to stimulate colony formation of hematopoietic progenitor cells in vitro and may, therefore, also modulate hematopoiesis.
Miyazawa K.,et al.Biochem. Biophys. Res. Commun. 163:967-973(1989).
Nakamura T.,et al.Nature 342:440-443(1989).
Seki T.,et al.Biochem. Biophys. Res. Commun. 172:321-327(1990).
Seki T.,et al.Gene 102:213-219(1991).
Miyazawa K.,et al.Eur. J. Biochem. 197:15-22(1991).
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