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Human CellExp IFN-alpha 2a, Human recombinant protein
Human Cellexp Human Recombinant IFN-alpha 2a
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P01563 |
|---|---|
| Calculated MW | 16 kDa, monomer, glycosylated |
| Gene ID | 3440 |
|---|---|
| Gene Symbol | IFNA2 |
| Other Names | Leukocyte interferon, B cell interferon, Type I interferon, IFNA2, IFN-α 2a. |
| Gene Source | Human |
| Source | Human 293 cell expressed |
| Assay&Purity | SDS-PAGE; ≥95% |
| Assay2&Purity2 | N/A; |
| Recombinant | Yes |
| Results | 0.1 to 0.4 ng/ml |
| Application Notes | Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin. |
| Format | Lyophilized |
| Storage | -80°C; Lyophilized from a TBS solution. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Interferons (IFNs) are proteins made and released by host cells in response to the presence of pathogens. They belong to the large class of glycoproteins known as cytokines. IFN-alpha is produced by macrophages and has antiviral activities. IFNs also have other functions: they activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes; and they increase the ability of uninfected host cells to resist new infection by virus.
References
Goeddel D.V.,et al.Nature 287:411-416(1980).
Goeddel D.V.,et al.Nature 290:20-26(1981).
Lawn R.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 78:5435-5439(1981).
Oliver G.,et al.Rev. Latinoam. Microbiol. 27:141-150(1985).
Austruy E.,et al.Cancer Gene Ther. 5:247-256(1998).
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