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Human CellExp IL-1beta, Human recombinant protein

Human Cellexp Human Recombinant IL-1beta

Product info
Primary Accession P01584
Calculated MW 18 and 25 kDa, monomer, glycosylated
Additional Info
Gene ID 3553
Gene Symbol IL1B
Other Names Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF), IL1F2, IL-1 beta.
Gene Source Human
Source Human 293 cell expressed
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant Yes
Results 0.02 to 0.08 ng/ml
Application Notes Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Format Lyophilized
Storage -80°C; Lyophilized from a PBS solution.
Citations (0)

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Interleukin-1beta is produced by activated macrophages. IL-1beta stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL1beta proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. In comparison with the E. coli expressed protein, IL-1 beta is 50% more potent in promoting human CD4+ T cell differentiation into Th17 cells. This cytokine is produced in a serumfree, chemically defined media.


Auron P.E.,et al.Proc. Natl. Acad. Sci. U.S.A. 81:7907-7911(1984).
March C.J.,et al.Nature 315:641-647(1985).
Clark B.D.,et al.Nucleic Acids Res. 14:7897-7914(1986).
Clark B.D.,et al.Nucleic Acids Res. 15:868-868(1987).
Nishida T.,et al.Biochem. Biophys. Res. Commun. 143:345-352(1987).

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$ 305.00
$ 1,180.00
Cat# PBV10692r
(40 western blots)
Availability: 5-7days
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