|Calculated MW||15 kDa, monomer, glycosylated|
|Other Names||T-cell growth factor (TCGF), Aldesleukin, Lymphokine, IL-2.|
|Source||Human 293 cell expressed|
|Results||0.2 to 2 ng/ml|
|Application Notes||Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.|
|Storage||-80°C; Lyophilized from a PBS solution.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
IL-2 is a potent immuno-modulator, which mediates a wide range of immune and inflammatory responses and is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
Maeda S.,et al.Biochem. Biophys. Res. Commun. 115:1040-1047(1983).
Taniguchi T.,et al.Nature 302:305-310(1983).
Devos R.,et al.Nucleic Acids Res. 11:4307-4323(1983).
Fujita T.,et al.Proc. Natl. Acad. Sci. U.S.A. 80:7437-7441(1983).
Holbrook N.J.,et al.Nucleic Acids Res. 12:5005-5013(1984).
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