|Calculated MW||14 and 19 kDa, monomer|
|Other Names||BCGF, BCDF, B cell stimulating factor, BSF-1, Lymphocyte stimulatory factor 1, IL-4, MGC79402, Binetrakin, Pitrakinra.|
|Source||Human 293 cell expressed|
|Results||0.1 to 0.5 ng/ml|
|Application Notes||Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.|
|Storage||-80°C; Lyophilized from a solution of 20 mM Tris-HCl, pH 7.4, with 300 mM NaCl.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
IL4 is a pleiotropic cytokine and a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. It is produced by activated T cells and is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Yokota T.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:5894-5898(1986).
Arai N.,et al.J. Immunol. 142:274-282(1989).
Klein S.C.,et al.Immunogenetics 41:57-57(1995).
Eder A.,et al.Nucleic Acids Res. 16:772-772(1988).
Carr C.,et al.Biochemistry 30:1515-1523(1991).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.