|Calculated MW||38 to 48 kDa, monomer, glycosylated|
|Other Names||P40, HP40, T-cell growth factor p40, IL-9, P40 cytokine.|
|Source||Human 293 cell expressed|
|Assay&Purity||SDS-PAGE; > 95%|
|Results||0.03 to 0.2 ng/ml|
|Application Notes||Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.|
|Storage||-80°C; Lyophilized from a PBS solution.|
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Provided below are standard protocols that you may find useful for product applications.
Interleukin 9 (IL-9) is cytokine produced by a subgroup of helper T cells, known as Th2 cells. IL-9 signals through its receptor IL-9R to induce cell proliferation and survival. Genetically, IL-9 has been identified as a gene associated with asthma. It is also thought to be a regulator of hematopoiesis. It has been shown to enhance the growth of human mast cells and megakaryoblastic leukemic cells as well as murine helper t-cell clones.
Yang Y.C.,et al.Blood 74:1880-1884(1989).
Renauld J.-C.,et al.Cytokine 2:9-12(1990).
Renauld J.-C.,et al.J. Immunol. 144:4235-4241(1990).
Kelleher K.,et al.Blood 77:1436-1441(1991).
Schmutz J.,et al.Nature 431:268-274(2004).
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