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Human CellExp IL-17F, Human recombinant protein

Human Cellexp Human Recombinant IL-17F

Product info
Primary Accession Q96PD4
Calculated MW 38 kDa, homodimer, glycosylated
Additional Info
Gene ID 112744
Gene Symbol IL17F
Other Names IL17A/F, IL17 A/F, IL-17A/F, IL-17 A/F, IL17AF, IL-17 AF, Interleukin-17 A/F, Interleukin-17 AF.
Gene Source Human
Source Human 293 cell expressed
Assay&Purity SDS-PAGE; > 95%
Assay2&Purity2 N/A;
Recombinant Yes
Results 100 to 500 ng/ml
Application Notes Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Format Lyophilized
Storage -80°C; Lyophilized in PBS.
Citations (0)

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Interleukin-17 is a proinflammatory cytokine produced by activated T cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. IL17 can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. IL-17F is a member of the IL-17 family of structurally-related cytokines. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F stimulates proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis.


Starnes T.,et al.J. Immunol. 167:4137-4140(2001).
Mungall A.J.,et al.Nature 425:805-811(2003).
Kawaguchi M.,et al.J. Immunol. 167:4430-4435(2001).
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).
Hymowitz S.G.,et al.EMBO J. 20:5332-5341(2001).

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$ 135.00
$ 540.00
Cat# PBV10701r
(40 western blots)
Availability: 5-7days
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