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Human CellExp IL-29, Human recombinant protein

Human Cellexp Human Recombinant IL-29

Product info
Primary Accession Q8IU54
Calculated MW 29 and 35 kDa, monomer, glycosylated
Additional Info
Gene ID 282618
Gene Symbol IFNL1
Other Names Interleukin-29, IL-29, IFN-Lambda 1, Interferon-Lambda 1, Cytokine ZCYTO21, IL29, IFNL1, ZCYTO21.
Gene Source Human
Source Human 293 cell expressed
Assay&Purity SDS-PAGE; > 95%
Assay2&Purity2 N/A;
Recombinant Yes
Results 0.5 to 5 ng/ml
Application Notes Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Format Lyophilized
Storage -80°C; Lyophilized in PBS.
Citations (0)

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IL-29 is distantly related to type I interferons and the IL-10 family. Expression of IL-29 is induced by viral infection which interacts with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor β (IL10RB) and interleukin 28 receptor α. IL-29 exhibits common features with type I IFNs such as antiviral activity, antiproliferative activity and in vivo antitumor activity. IL-29 acts similarly to IFNs, but is less effective generally and has activity in a more limited range of cell lines. IL-29 produced in response to viral infection, activates both monocytes and macrophages producing a restricted panel of cytokines and therefore is an important factor in activating innate immune responses at the site of viral infection. IFN-Lambda 1 antiviral and antiproliferative activity requires Interferon-Lambda 2 receptor tyrosine residues.


Sheppard P.,et al.Nat. Immunol. 4:63-68(2003).
Kotenko S.V.,et al.Nat. Immunol. 4:69-77(2003).
Li M.,et al.Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
Grimwood J.,et al.Nature 428:529-535(2004).
Donnelly R.P.,et al.J. Interferon Cytokine Res. 30:555-564(2010).

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$ 270.00
$ 1,180.00
Cat# PBV10705r
(40 western blots)
Availability: 5-7days
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