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Human CellExp SCF, Human recombinant protein

Human Cellexp Human Recombinant SCF

     
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  • CITATIONS
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Product info
Primary Accession P21583
Calculated MW 35 to 45 kDa, monomer, glycosylated
Additional Info
Gene ID 4254
Gene Symbol KITLG
Other Names Kit ligand Precursor, C-kit ligand, SCF, Mast cell growth factor, MGF, SF, KL-1, Kit l, DKFZp686F2250.
Gene Source Human
Source Human 293 cell expressed
Assay&Purity SDS-PAGE; > 95%
Assay2&Purity2 N/A;
Recombinant Yes
Results 5 to 25 ng/ml
Application Notes Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Format Lyophilized
Storage -80°C; Lyophilized in PBS.
Citations (0)

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Background

Stem cell factor / KIT ligand (SCF) is a cytokine which binds CD117(c-Kit). SCF is also known as "steel factor" or "c-kit ligand". SCF exists in two forms; cell surface bound SCF and soluble (or free) SCF. Soluble SCF is produced by the cleavage of surface bound SCF by metalloproteases. SCF is a growth factor important for the survival, proliferation, and differentiation of hematopoietic stem cells and other hematopoietic progenitor cells. One of its roles is to change the BFU-E (burst-forming unit-erythroid) cells, which are the earliest erythrocyte precursors in the erythrocytic series, into the CFU-E (colony-forming unit-erythroid).

References

Martin F.H.,et al.Cell 63:203-211(1990).
Anderson D.M.,et al.Cell Growth Differ. 2:373-378(1991).
Blair H.C.,et al.Biochem. Biophys. Res. Commun. 255:778-784(1999).
Han C.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 270.00
$ 1,180.00
Cat# PBV10710r
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