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Human CellExp TGF-beta 1, Human recombinant protein
Human Cellexp Human Recombinant TGF-beta 1
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P01137 |
|---|---|
| Calculated MW | 25 kDa, homodimer, nonglycosylated |
| Gene ID | 7040 |
|---|---|
| Gene Symbol | TGFB1 |
| Other Names | Transforming growth factor beta-1, TGF-beta-1, CED, DPD1, TGFB, TGF-b 1, LAP, TGFB1. |
| Gene Source | Human |
| Source | Human 293 cell expressed |
| Assay&Purity | SDS-PAGE; > 95% |
| Assay2&Purity2 | N/A; |
| Recombinant | Yes |
| Results | 0.1 to 0.5 ng/ml |
| Application Notes | Reconstitute in sterile 4 mM HCl containing 0.1% endotoxin-free recombinant human serum albumin. |
| Format | Lyophilized |
| Storage | -80°C; Lyophilized from 50 mM sodium acetate, pH 4.5 and 350 mM NaCl. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Transforming growth factor betas (TGFβ) mediate many cell-cell interactions that occur during embryonic development. Three TGFβs have been identified in mammals. TGF Beta 1, TGF Beta 2 and TGF Beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. TGF-beta 1 is involved in hematopoiesis and endothelial differentiation.
References
Derynck R.,et al.Nucleic Acids Res. 15:3188-3189(1987).
Derynck R.,et al.Nature 316:701-705(1985).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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