|Calculated MW||25 kDa, homodimer, nonglycosylated|
|Other Names||Transforming Growth Factor-beta3, TGFB3, ARVD, FLJ16571, TGF-beta 3.|
|Source||Human 293 cell expressed|
|Assay&Purity||SDS-PAGE; > 95%|
|Results||0.1 to 0.5 ng/ml|
|Application Notes||Reconstitute in sterile 4 mM HCl containing 0.1% endotoxin-free recombinant human serum albumin.|
|Storage||-80°C; Lyophilized from 50 mM sodium acetate, pH 4.5 and 350 mM NaCl.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Transforming growth factor betas (TGFβ) mediate many cell-cell interactions that occur during embryonic development. Three TGFβs have been identified in mammals. TGF Beta 1, TGF Beta 2 and TGF Beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. TGF-beta 3 influences pathogenesis and pulmonary development.
ten Dijke P.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:4715-4719(1988).
Derynck R.,et al.EMBO J. 7:3737-3743(1988).
Madan A.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Heilig R.,et al.Nature 421:601-607(2003).
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