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Human CellExp TPO, Human recombinant protein

Human Cellexp Human Recombinant TPO

     
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Product info
Primary Accession P40225
Calculated MW 80 to 85 kDa, monomer, glycosylated
Additional Info
Gene ID 7066
Gene Symbol THPO
Other Names Megakaryocyte colony-stimulating factor, Myeloproliferative leukemia virus oncogene ligand, C-mpl ligand, ML, Megakaryocyte growth and development factor, MGDF, TPO, MKCSF, MPLLG, MGC163194, THPO.
Gene Source Human
Source Human 293 cell expressed
Assay&Purity SDS-PAGE; > 95%
Assay2&Purity2 N/A;
Recombinant Yes
Results 0.5 to 5 ng/ml
Application Notes Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Format Lyophilized
Storage -80°C; Lyophilized in PBS.
Citations (0)

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Background

TPO (Thrombopoietin, also known as Mpl-ligand, MGDF), a glycoprotein hormone produced mainly by the liver and the kidney, stimulates the proliferation and maturation of megakaryocytes and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets.

References

de Sauvage F.J.,et al.Nature 369:533-538(1994).
Bartley T.D.,et al.Cell 77:1117-1124(1994).
Foster D.C.,et al.Proc. Natl. Acad. Sci. U.S.A. 91:13023-13027(1994).
Sohma Y.,et al.FEBS Lett. 353:57-61(1994).
Gurney A.L.,et al.Blood 85:981-988(1995).

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$ 290.00
$ 1,775.00
Cat# PBV10715r
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