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Human CellExp VEGF 121, Human recombinant protein

Human Cellexp Human Recombinant VEGF 121

Product info
Primary Accession P15692
Calculated MW 37 kDa, homodimer; 50 kDa, homotrimer, glycosylated
Additional Info
Gene ID 7422
Gene Symbol VEGFA
Other Names Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, VEGF, MGC70609.
Gene Source Human
Source Human 293 cell expressed
Assay&Purity SDS-PAGE; > 95%
Assay2&Purity2 N/A;
Recombinant Yes
Results 2 to 8 ng/ml
Application Notes Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Format Lyophilized
Storage -80°C; Lyophilized in PBS.
Citations (0)

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VEGF is an important signaling protein involved in both vasculogenesis and angiogenesis. As its name implies, VEGF activity has been mostly studied on cells of the vascular endothelium, although it does have effects on a number of other cell types (e.g. stimulation monocyte/ macrophage migration, neurons, cancer cells, kidney epithelial cells).VEGF mediates increased vascular permeability, induces angiogenesis, vasculogenesis and endothelial cell growth, promotes cell migration, and inhibits apoptosis. In vitro, VEGF has been shown to stimulate endothelial cell mitogenesis and cell migration. VEGF is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor. Elevated levels of this protein are linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy.


Leung D.W.,et al.Science 246:1306-1309(1989).
Keck P.J.,et al.Science 246:1309-1312(1989).
Tischer E.,et al.J. Biol. Chem. 266:11947-11954(1991).
Houck K.A.,et al.Mol. Endocrinol. 5:1806-1814(1991).
Weindel K.,et al.Biochem. Biophys. Res. Commun. 183:1167-1174(1992).

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$ 270.00
$ 1,180.00
Cat# PBV10716r
(40 western blots)
Availability: 5-7days
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