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c-Jun (1-79)-GST Fusion Protein recombinant protein


Product info
Primary Accession P05412
Concentration 2
Calculated MW 37.0 kDa
Additional Info
Gene ID 3725
Gene Symbol JUN; AP1; c-Jun
Other Names Transcription factor AP-1, (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 HPLC;
Recombinant Yes
Format Liquid
Storage -20°C; 2 mg/ml in storage buffer containing 20 mM Tris-HCl (pH 7.5), 50 mM NaCl, 2 mM EDTA, 1 mM DTT, and 50% glycerol.
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c-Jun is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins, and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. The MAP kinase homologue, JNK, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. The activity of JNK is stimulated by the same signals that activates c-Jun.

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$ 145.00
Cat# PBV10732r
(40 western blots)
Availability: 5-7days
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