|Calculated MW||37.0 kDa|
|Other Names||GSK, Glycogen synthase kinase-3 (GSK-3)|
|Storage||-20°C; 2 mg/ml in storage buffer containing 20 mM Tris-HCl (pH 7.5), 50 mM NaCl, 2 mM EDTA, 1 mM DTT, and 50% glycerol.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
GSK-3 is one of the Akt substrates. It can be phosphorylated by Akt at Ser21 of GSK-3α or Ser9 of GSK-3β. The phosphorylation of GSK negatively regulates its kinase activity. The recombinant GSK-3α fusion protein serves as a useful substrate for assaying Akt kinase activity.
He X.,et al.Submitted (MAR-1995) to the EMBL/GenBank/DDBJ databases.
Hoshino T.,et al.Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.
Grimwood J.,et al.Nature 428:529-535(2004).
Nikoulina S.E.,et al.Diabetes 49:263-271(2000).
Phiel C.J.,et al.Nature 423:435-439(2003).
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