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Activin B, Human recombinant protein

Activin beta-B, Inhibin beta-2

     
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  • CITATIONS
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Product info
Primary Accession P36896
Calculated MW 25.6 kDa
Additional Info
Gene ID 91
Gene Symbol ACVR1B
Other Names Activin beta-B, Inhibin beta-2
Gene Source Human
Source (BTI-Tn-5B1-4) Hi-5 Insect cells
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 HPLC;
Recombinant Yes
Sequence GLECDGRTNL CCRQQFFIDF RLIGWNDWII APTGYYGNYC EGSCPAYLAG VPGSASSFHT AVVNQYRMRG LNPGTVNSCC IPTKLSTMSM LYFDDEYNIV KRDVPNMIVE ECGCA
Target/Specificity Activin B
Application Notes Centrifuge the vial prior to opening. Reconstitute in 10 mM Sodium citrate, pH 3.0 to a concentration of 0.5 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Format Lyophilized powder
Storage -20°C; Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Sodium Citrate, pH 3.0 and 5% Trehalose.
Citations (0)

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Background

Activin B is a TGF-β family member that exhibits a wide range of biological activities including regulation of embryogenesis, osteogenesis, hematopoiesis, reproductive physiology and hormone secretion from the hypothalamic, pituitary and gonadal glands. Activin B, like certain other members of the TGF-β family, signals through the ActRII receptor (Activin Receptor type II). Human Activin B is a 25.6 kDa disulfide-linked homodimer consisting of two βB chains, each containing 115 amino acid residues.

References

ten Dijke P.,et al.Oncogene 8:2879-2887(1993).
Carcamo J.,et al.Mol. Cell. Biol. 14:3810-3821(1994).
Xu J.,et al.Proc. Natl. Acad. Sci. U.S.A. 91:7957-7961(1994).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
$ 1,880.00
Cat# PBV10747r-10
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