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sCD23, Human recombinant protein

CD23 antigen, Fc-epsilon-RII, Lymphocyte IgE receptor, BLAST-2

     
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Product info
Primary Accession Q30218
Calculated MW 19.2 kDa
Additional Info
Gene ID 9606
Gene Symbol CD23
Other Names CD23 antigen, Fc-epsilon-RII, Lymphocyte IgE receptor, BLAST-2
Gene Source Human
Source E.coli
Assay&Purity SDS-PAGE; ≥96%
Assay2&Purity2 HPLC;
Recombinant Yes
Sequence MELQVSSGFV CNTCPEKWIN FQRKCYYFGK GTKQWVHARY ACDDMEGQLV SIHSPEEQDF LTKHASHTGS WIGLRNLDLK GEFIWVDGSH VDYSNWAPGE PTSRSQGEDC VMMRGSGRWN DAFCDRKLGA WVCDRLATCT PPASEGSAES MGPDSRPDPD GRLPTPSAPL HS
Target/Specificity sCD23
Application Notes Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Format Lyophilized powder
Storage -20°C; Sterile filtered through a 0.2 micron filter. Lyophilized from 0.5X PBS, pH 8.0.
Citations (0)

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Background

CD23, the low affinity receptor for IgE, belongs to the C-type lectin structural family and plays a role in the regulation of IgE synthesis and IgE mediated activities. It is found both as a transmembrane receptor protein and in a soluble form, which is generated by proteolytic cleavage of membrane bound CD23. The predominant soluble form of CD23 (sCD23) consists of 172 amino acids corresponding to the extracellular domain of the full length precursor. sCD23, in addition to binding IgE, also exerts a number of IgE independent activities, such as promoting the activation and differentiation of B-cells and stimulating the release of pro-inflammatory cytokines from monocytes. Recombinant human sCD23 is a 19.2 kDa non-glycosylated protein containing 172 amino-acid residues.

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$ 145.00
$ 575.00
Cat# PBV10759r
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