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FGF-5, human recombinant protein

Fibroblast Growth Factor-5, HBGF-5, Smag-82

     
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Product info
Primary Accession P12034
Calculated MW 27.6 kDa
Additional Info
Gene ID 2250
Gene Symbol FGF5
Other Names Fibroblast Growth Factor-5, HBGF-5, Smag-82
Gene Source Human
Source E.coli
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 HPLC;
Recombinant Yes
Sequence MAWAHGEKRL APKGQPGPAA TDRNPIGSSS RQSSSSAMSS SSASSSPAAS LGSQGSGLEQ SSFQWSPSGR RTGSLYCRVG IGFHLQIYPD GKVNGSHEAN MLSVLEIFAV SQGIVGIRGV FSNKFLAMSK KGKLHASAKF TDDCKFRERF QENSYNTYAS AIHRTEKTGR EWYVALNKRG KAKRGCSPRV KPQHISTHFL PRFKQSEQPE LSFTVTVPEK KNPPSPIKSK IPLSAPRKNT NSVKYRLKFR FG
Target/Specificity FGF-5
Application Notes Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Format Lyophilized powder
Storage -20°C; Sterile filtered through a 0.2 micron filter. Lyophilized from 5 mM Tris, pH 7.5, and 25 mM NaCl.
Citations (0)
citation

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Background

FGF-5 is a secreted heparin binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-5 binds to FGFR 1c and 2c, and plays a regulatory role in the hair growth cycle. Recombinant human FGF-5 is a 27.6 kDa protein consisting of 252 amino acid residues.

References

Haub O.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:8022-8026(1990).
Zhan X.,et al.Mol. Cell. Biol. 8:3487-3495(1988).
Ozawa K.,et al.Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases.
de Vries C.J.M.,et al.J. Biol. Chem. 275:23939-23947(2000).
Hanada K.-I.,et al.Cancer Res. 61:5511-5516(2001).

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Discontinued
Cat# PBV10777r-10
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