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FGF-16, human recombinant protein
Fibroblast Growth Factor-16, FGFG
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O43320 |
|---|---|
| Calculated MW | 23.6 kDa |
| Gene ID | 8823 |
|---|---|
| Gene Symbol | FGF16 |
| Other Names | Fibroblast Growth Factor-16, FGFG |
| Gene Source | Human |
| Source | E.coli |
| Assay&Purity | SDS-PAGE; ≥95% |
| Assay2&Purity2 | HPLC; |
| Recombinant | Yes |
| Sequence | AEVGGVFASL DWDLHGFSSS LGNVPLADSP GFLNERLGQI EGKLQRGSPT DFAHLKGILR RRQLYCRTGF HLEIFPNGTV HGTRHDHSRF GILEFISLAV GLISIRGVDS GLYLGMNERG ELYGSKKLTR ECVFREQFEE NWYNTYASTL YKHSDSERQY YVALNKDGSP REGYRTKRHQ KFTHFLPRPV DPSKLPSMSR DLFHYR |
| Target/Specificity | FGF-16 |
| Application Notes | FGF-16 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-16 signals through FGFR 2c and 3c. FGF-16 plays a role in the development of the central nervous system. Recombinant human FGF-16 is a 23.6 kDa protein consisting of 206 amino acid residues. |
| Format | Lyophilized powder |
| Storage | -20°C; Sterile filtered through a 0.2 micron filter. Lyophilized from 5 mM Tris, pH 9.0, 0.1 M L-Arginine and 0.4 mM DTT. |
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Provided below are standard protocols that you may find useful for product applications.
Background
FGF-16 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-16 signals through FGFR 2c and 3c. FGF-16 plays a role in the development of the central nervous system. Recombinant human FGF-16 is a 23.6 kDa protein consisting of 206 amino acid residues.
References
Miyake A.,et al.Biochem. Biophys. Res. Commun. 243:148-152(1998).
Ross M.T.,et al.Nature 434:325-337(2005).
Zhang X.,et al.J. Biol. Chem. 281:15694-15700(2006).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
Turner N.,et al.Nat. Rev. Cancer 10:116-129(2010).
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