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FGF-17, human recombinant protein

Fibroblast Growth Factor-17, FGFH

     
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Product info
Primary Accession O60258
Calculated MW 22.7 kDa
Additional Info
Gene ID 8822
Gene Symbol FGF17
Other Names Fibroblast Growth Factor-17, FGFH
Gene Source Human
Source E.coli
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 HPLC;
Recombinant Yes
Sequence MTQGENHPSP NFNQYVRDQG AMTDQLSRRQ IREYQLYSRT SGKHVQVTGR RISATAEDGN KFAKLIVETD TFGSRVRIKG AESEKYICMN KRGKLIGKPS GKSKDCVFTE IVLENNYTAF QNARHEGWFM AFTRQGRPRQ ASRSRQNQRE AHFIKRLYQG QLPFPNHAEK QKQFEFVGSA PTRRTKRTRR PQPLT
Target/Specificity FGF-17
Application Notes Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Format Lyophilized powder
Storage -20°C; Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM sodium phosphate, pH 8.0 and 50 mM NaCl.
Citations (0)

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Background

FGF-17 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-17 signals through the FGFR 1c, 2c, 3c, and 4. FGF-17 signals induction and patterning of embryonic brain. Recombinant human FGF-17 is a 22.7 kDa protein consisting of 195 amino acid residues.

References

Hoshikawa M.,et al.Biochem. Biophys. Res. Commun. 244:187-191(1998).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Zhang X.,et al.J. Biol. Chem. 281:15694-15700(2006).
Turner N.,et al.Nat. Rev. Cancer 10:116-129(2010).

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$ 145.00
$ 575.00
Cat# PBV10780r-10
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