GCP-2 (CXCL6), human recombinant protein
CXCL6
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P80162 |
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Calculated MW | 7.9 kDa |
Gene ID | 6372 |
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Gene Symbol | CXCL3 |
Other Names | CXCL6 |
Gene Source | Human |
Source | E.coli |
Assay&Purity | SDS-PAGE; ≥98% |
Assay2&Purity2 | HPLC; |
Recombinant | Yes |
Sequence | VLTELRCTCL RVTLRVNPKT IGKLQVFPAG PQCSKVEVVA SLKNGKQVCL DPEAPFLKKV IQKILDSGNK KN |
Target/Specificity | CXCL6 |
Application Notes | Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C. |
Format | Lyophilized powder |
Storage | -20°C; Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM acetic acid. |
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Provided below are standard protocols that you may find useful for product applications.
Background
GCP-2 is a connective tissue derived CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. GCP-2 selectively attracts neutrophils and has also been shown to exert angiogenic activity. Human GCP-2 is cross-react on murine cells. Recombinant human GCP-2 is a 7.9 kDa protein containing 72 amino acid residues.
References
Rovai L.E.,et al.J. Immunol. 158:5257-5266(1997).
Ni J.,et al.Submitted (DEC-1996) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Froyen G.,et al.Eur. J. Biochem. 243:762-769(1997).
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