|Calculated MW||12.3 kDa|
|Other Names||Mucosae-associated Epithelial Chemokine, CCL28, CCK-1|
|Sequence||SEAILPIASS CCTEVSHHIS RRLLERVNMC RIQRADGDCD LAAVILHVKR RRICVSPHNH TVKQWMKVQA AKKNGKGNVC HRKKHHGKRN SNRAHQGKHE TYGHKTPY|
|Application Notes||Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.|
|Storage||-20°C; Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Acetic Acid.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
MEC is a secreted CC chemokine expressed primarily by epithelial cells of the bronchioles, salivary gland, mammary gland and colon. MEC signals through the CCR10 receptor and chemoattracts resting CD4, CD8 T cells and eosinophils. MEC contains six cysteines including the four highly conserved cysteine residues present in CC chemokines. Recombinant human MEC is a 12.3 kDa protein containing 108 amino acid residues.
Wang W.,et al.J. Biol. Chem. 275:22313-22323(2000).
Pan J.,et al.J. Immunol. 165:2943-2949(2000).
Zhang W.,et al.Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
Scanlon K.M.,et al.Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
Schmutz J.,et al.Nature 431:268-274(2004).
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