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MEC/CCL28, human recombinant protein

Mucosae-associated Epithelial Chemokine, CCL28, CCK-1

     
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  • CITATIONS
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Product info
Primary Accession Q9NRJ3
Calculated MW 12.3 kDa
Additional Info
Gene ID 56477
Gene Symbol CCL28
Other Names Mucosae-associated Epithelial Chemokine, CCL28, CCK-1
Gene Source Human
Source E. Coli
Assay&Purity SDS-PAGE; ≥98%
Assay2&Purity2 HPLC;
Recombinant Yes
Sequence SEAILPIASS CCTEVSHHIS RRLLERVNMC RIQRADGDCD LAAVILHVKR RRICVSPHNH TVKQWMKVQA AKKNGKGNVC HRKKHHGKRN SNRAHQGKHE TYGHKTPY
Target/Specificity CCL28
Application Notes Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Format Lyophilized powder
Storage -20°C; Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Acetic Acid.
Citations (0)

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Background

MEC is a secreted CC chemokine expressed primarily by epithelial cells of the bronchioles, salivary gland, mammary gland and colon. MEC signals through the CCR10 receptor and chemoattracts resting CD4, CD8 T cells and eosinophils. MEC contains six cysteines including the four highly conserved cysteine residues present in CC chemokines. Recombinant human MEC is a 12.3 kDa protein containing 108 amino acid residues.

References

Wang W.,et al.J. Biol. Chem. 275:22313-22323(2000).
Pan J.,et al.J. Immunol. 165:2943-2949(2000).
Zhang W.,et al.Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
Scanlon K.M.,et al.Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
Schmutz J.,et al.Nature 431:268-274(2004).

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$ 145.00
$ 575.00
Cat# PBV10800r
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