|Calculated MW||7.8 kDa|
|Other Names||Macrophage Inflammatory Protein-1γ, CCL9/10, MRP2, CCF18|
|Sequence||QITHATETKE VQSSLKAQQG LEIEMFHMGF QDSSDCCLSY NSRIQCSRFI GYFPTSGGCT RPGIIFISKR GFQVCANPSD RRVQRCIERL EQNSQPRTYK Q|
|Application Notes||Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.|
|Storage||-20°C; Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.|
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Provided below are standard protocols that you may find useful for product applications.
MIP-1γ is a CC chemokine found in murine blood and a wide variety of murine tissues, with no known human homolog. MIP-1γ signals through the CCR1 receptor. MIP-1γ chemoattracts neutrophils and also inhibits colony formation of bone marrow myeloid immature progenitors. MIP-1γ contains six cysteines including the four highly conserved cysteine residues present in CC chemokines. Recombinant murine MIP-1γ is an 11.6 kDa protein containing 101 amino acid residues.
Poltorak A.N.,et al.J. Inflamm. 45:207-219(1995).
Youn B.-S.,et al.J. Immunol. 155:2661-2667(1995).
Hara T.,et al.J. Immunol. 155:5352-5358(1995).
Teuscher C.,et al.J. Immunol. 163:2262-2266(1999).
Nomiyama H.,et al.Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.
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