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Nesfatin-1, human recombinant protein

Nesfatin 1

     
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  • CITATIONS
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Product info
Primary Accession P80303
Calculated MW 9.7 kDa
Additional Info
Gene ID 4925
Gene Symbol NEFA
Other Names Nesfatin 1
Gene Source Human
Source E. Coli
Assay&Purity SDS-PAGE; ≥98%
Assay2&Purity2 HPLC;
Recombinant Yes
Sequence VPIDIDKTKV QNIHPVESAK IEPPDTGLYY DEYLKQVIDV LETDKHFREK LQKADIEEIK SGRLSKELDL VSHHVRTKLD EL
Target/Specificity Nesfatin-1
Application Notes Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Format Lyophilized powder
Storage -20°C; Sterile filtered through a 0.2 micron filter. Lyophilized from 0.1% TFA
Citations (0)

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Background

Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2). Originally identified as a hypothalamic neuropeptide, Nesfatin-1 is also expressed in other areas of the brain, and in pancreatic islets β-cells, gastric endocrine cells and adipocytes. Nesfatin-1 suppresses food intake and can regulate energy metabolism in a Leptin independent manner. Recombinant human Nesfatin-1 is a 9.7 kDa protein containing 82 amino acid residues.

References

Barnikol-Watanabe S.,et al.Biol. Chem. Hoppe-Seyler 375:497-512(1994).
Deangelis M.M.,et al.Biochim. Biophys. Acta 1407:84-91(1998).
Line A.,et al.Br. J. Cancer 86:1824-1830(2002).
Yamada M.,et al.Endocrinology 151:2494-2503(2010).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 80.00
$ 205.00
Cat# PBV10808r-10
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