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Relaxin-2, human recombinant protein

H2 relaxin, RLN2

Product info
Primary Accession P04090
Calculated MW 6.0 kDa
Additional Info
Gene ID 6019
Gene Symbol RLN2
Other Names H2 relaxin, RLN2
Gene Source Human
Source E. Coli
Assay&Purity SDS-PAGE; ≥98%
Assay2&Purity2 HPLC;
Recombinant Yes
Target/Specificity Relaxin-2
Application Notes Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Format Lyophilized powder
Storage -20°C; Sterile filtered through a 0.2 micron filter. Lyophilized with no additives
Citations (0)

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Relaxin-2 is a peptide hormone structurally related to insulin, which is expressed in the placenta, decidua, prostate, and in the ovary during pregnancy. Of the three known relaxin genes, Relaxin-2 is the only relaxin known to circulate in the blood. Relaxin-2 binds specifically to the LGR7 and LGR8 receptors, previously identified as an “orphan” G protein coupled receptors. Signaling by Relaxin-2 through its target receptors enhances the growth of pubic ligaments and ripening of the cervix during birth. Recombinant Relaxin-2 is a nonglycosylated 6.0 kDa disulfide linked heterodimeric protein consisting of a 24 amino acid A-chain and a 29 amino acid B-chain.


Hudson P.,et al.EMBO J. 3:2333-2339(1984).
Humphray S.J.,et al.Nature 429:369-374(2004).
Gunnersen J.M.,et al.Mol. Cell. Endocrinol. 118:85-94(1996).
Garibay-Tupas J.L.,et al.J. Mol. Endocrinol. 23:355-365(1999).
Winslow J.W.,et al.Endocrinology 130:2660-2668(1992).

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$ 145.00
$ 575.00
Cat# PBV10824r
(40 western blots)
Availability: 5-7days
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