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>   home   >   Products   >   Proteins   >   Human CellExp PLGF/PIGF2/PGF, human recombinant protein   

Human CellExp PLGF/PIGF2/PGF, human recombinant protein


Product info
Primary Accession P49763
Calculated MW The protein is fused with 6×His tag at the C-terminus, has a calculated MW of 20.2 kDa. The predicted N-terminus is Leu 19. DTT-reduced Protein migrates as 28-33 kDa due to glycosylation.
Additional Info
Gene ID 5228
Gene Symbol PLGF
Other Names PGF, PLGF, PlGF2, PlGF, PGFL, SHGC-10760
Gene Source Human
Source HEK 293 cells
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 HPLC;
Recombinant Yes
Target/Specificity PLGF
Application Notes Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
Format Lyophilized powder
Storage -20°C; Lyophilized from 0.22 µm filtered solution in PBS. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.
Citations (0)

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Placental growth factor (PGF) also known as vascular endothelial growth factor-related protein, PLGF and PlGF2, is a member of the VEGF (vascular endothelial growth factor) sub-family - a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast. PGF is actived in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. PlGF2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.


Maglione D.,et al.Proc. Natl. Acad. Sci. U.S.A. 88:9267-9271(1991).
Hauser S.D.,et al.Growth Factors 9:259-268(1993).
Maglione D.,et al.Oncogene 8:925-931(1993).
Cao Y.,et al.Biochem. Biophys. Res. Commun. 235:493-498(1997).
Heilig R.,et al.Nature 421:601-607(2003).

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$ 375.00
Cat# PBV10868r
(40 western blots)
Availability: 5-7days
Bulk Size
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