Human CellExp CD71 / TFRC / TFR, human recombinant protein
CD71, TFRC, TFR, sTfR, TfR1, Trfr, T9, p90
|Calculated MW||This protein is fused with 6×His tag at the N-terminus, has a calculated MW of 76 kDa. The predicted N-terminus is Cys 89. DTT-reduced Protein migrates as 80-85 kDa due to glycosylation.|
|Other Names||CD71, TFRC, TFR, sTfR, TfR1, Trfr, T9, p90|
|Results||Measured by its binding ability in a functional ELISA. Immobilized rhCD71/TFR at 10 µg/ml (100 µl/well) can bind human Transferrin. The EC50 of human Transferrin is 6.4 ng/ml.|
|Target/Specificity||CD71 /TFRC /TFR|
|Application Notes||Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.|
|Storage||-20°C; Lyophilized from 0.22 µm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.|
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Provided below are standard protocols that you may find useful for product applications.
CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukemia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.
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Wheeler D.L.,et al.Thesis (1999), University of Iowa, United States.
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
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