CD79B, human recombinant protein
CD79b molecule, immunoglobulin-associated beta, AGM6, B29, IGB
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P40259 |
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Concentration | 1 |
Calculated MW | 17.7 kDa (155 aa, 29-159 aa + His tag), confirmed by MALDI-TOF. |
Gene ID | 974 |
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Gene Symbol | CD79B |
Other Names | CD79b molecule, immunoglobulin-associated beta, AGM6, B29, IGB |
Gene Source | Human |
Source | E. coli |
Assay&Purity | SDS-PAGE; ≥90% |
Assay2&Purity2 | N/A; |
Recombinant | Yes |
Sequence | MGSSHHHHHH SSGLVPRGSH MGSMARSEDR YRNPKGSACS RIWQSPRFIA RKRGFTVKMH CYMNSASGNV SWLWKQEMDE NPQQLKLEKG RMEESQNESL ATLTIQGIRF EDNGIYFCQQ KCNNTSEVYQ GCGTELRVMG FSTLAQLKQR NTLKD |
Target/Specificity | CD79B |
Format | Liquid |
Storage | -80°C; 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 2 M Urea and 10% glycerol. |
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Provided below are standard protocols that you may find useful for product applications.
Background
CD79B, also known as Igb and B29, is a 36 kDa transmembrane glycoprotein in the immunoglobulin superfamily. Heterodimers of CD79A and CD79B associate with a membrane bound immunoglobulin on the B cell surface to form the B cell antigen receptor complex (BCR). CD79A and CD79B are required for BCR-mediated signaling and consequently for the development and activation of B lineage cells. Recombinant human CD79B protein, fused to His-tag at N-terminus, was expressed in E.coli.
References
Mueller B.S.,et al.Eur. J. Immunol. 22:1621-1625(1992).
Wood W.J. Jr.,et al.Genomics 16:187-192(1993).
Hashimoto S.,et al.J. Immunol. 150:491-498(1993).
Hashimoto S.,et al.Immunogenetics 40:145-149(1994).
Hashimoto S.,et al.Mol. Immunol. 32:651-659(1995).
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