|Calculated MW||17.7 kDa (155 aa, 29-159 aa + His tag), confirmed by MALDI-TOF.|
|Other Names||CD79b molecule, immunoglobulin-associated beta, AGM6, B29, IGB|
|Sequence||MGSSHHHHHH SSGLVPRGSH MGSMARSEDR YRNPKGSACS RIWQSPRFIA RKRGFTVKMH CYMNSASGNV SWLWKQEMDE NPQQLKLEKG RMEESQNESL ATLTIQGIRF EDNGIYFCQQ KCNNTSEVYQ GCGTELRVMG FSTLAQLKQR NTLKD|
|Storage||-80°C; 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 2 M Urea and 10% glycerol.|
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Provided below are standard protocols that you may find useful for product applications.
CD79B, also known as Igb and B29, is a 36 kDa transmembrane glycoprotein in the immunoglobulin superfamily. Heterodimers of CD79A and CD79B associate with a membrane bound immunoglobulin on the B cell surface to form the B cell antigen receptor complex (BCR). CD79A and CD79B are required for BCR-mediated signaling and consequently for the development and activation of B lineage cells. Recombinant human CD79B protein, fused to His-tag at N-terminus, was expressed in E.coli.
Mueller B.S.,et al.Eur. J. Immunol. 22:1621-1625(1992).
Wood W.J. Jr.,et al.Genomics 16:187-192(1993).
Hashimoto S.,et al.J. Immunol. 150:491-498(1993).
Hashimoto S.,et al.Immunogenetics 40:145-149(1994).
Hashimoto S.,et al.Mol. Immunol. 32:651-659(1995).
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