|Calculated MW||25.4 kDa (229 aa, 22-225 aa + His tag), confirmed by MALDI-TOF.|
|Other Names||SLAM family member 5, hCD84, LY9B, mCD84, SLAMF5|
|Sequence||MGSSHHHHHH SSGLVPRGSH MGSHM ALGPNYNLVI SDLRMEDAGD YKADINTQAD PYTTTKRYNL QIYRRLGKPK ITQSLMASVN STCNVTLTCS VEKEEKNVTY NWSPLGEEGN KDSEI FTVNGILGES VTFPVNIQEP RQVKIIAWTS KTSVAYVTPG DSETAPVVTV THRNYYERIH VLQIFQTPED QELTYTCTAQ NPVSNNSDSI SARQLCADIA MGFRTHHTG|
|Storage||-80°C; 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol.|
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Provided below are standard protocols that you may find useful for product applications.
CD84 is a membrane glycoprotein that is a member of the signaling lymphocyte activation molecule (SLAM) family. This family forms a subset of the larger CD2 cell-surface receptor Ig superfamily. The protein is a hemophilic adhesion molecule that is expressed in numerous immune cells types and is involved in regulating receptor-mediated signaling in those cells. Recombinant human CD84 protein, fused to His-tag at N-terminus, was expressed in E.coli.
de la Fuente M.A.,et al.Blood 90:2398-2405(1997).
Krause S.W.,et al.Biochem. J. 346:729-736(2000).
Palou E.,et al.Tissue Antigens 55:118-127(2000).
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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