CD8B, human recombinant protein
T-cell surface glycoprotein CD8 beta chain isoform 5 precursor, CD8B1, LEU2, LY3, LYT3, P37
|Calculated MW||19.2 kDa (172 aa, 22-170 aa + His tag), confirmed by MALDI-TOF.|
|Other Names||T-cell surface glycoprotein CD8 beta chain isoform 5 precursor, CD8B1, LEU2, LY3, LYT3, P37|
|Sequence||MGSSHHHHHH SSGLVPRGSH MGSLQQTPAY IKVQTNKMVM LSCEAKISLS NMRIYWLRQR QAPSSDSHHE FLALWDSAKG TIHGEEVEQE KIAVFRDASR FILNLTSVKP EDSGIYFCMI VGSPELTFGK GTQLSVVDFL PTTAQPTKKS TLKKRVCRLP RPETQKGPLC SP|
|Storage||-80°C; 0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Recombinant human CD8B protein, fused to His-tag at N-terminus, was expressed in E.coli.
Norment A.M.,et al.EMBO J. 7:3433-3439(1988).
Disanto J.P.,et al.EMBO J. 7:3465-3470(1988).
Shiue L.,et al.J. Exp. Med. 168:1993-2005(1988).
Nakayama K.,et al.J. Immunol. 148:1919-1927(1992).
Hillier L.W.,et al.Nature 434:724-731(2005).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.