|Calculated MW||15 kDa (134 aa, 1-114 aa + His tag), confirmed by MALDI-TOF.|
|Other Names||Interferon regulatory factor-1, MAR|
|Sequence||MGSSHHHHHH SSGLVPRGSH MPITRMRMRP WLEMQINSNQ IPGLIWINKE EMIFQIPWKH AAKHGWDINK DACLFRSWAI HTGRYKAGEK EPDPKTWKAN FRCAMNSLPD IEEVKDQSRN KGSSAVRVYR MLPP|
|Storage||-80°C; 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) and 10% glycerol.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
IRF1, Interferon regulatory factor 1, is a member of the interferon regulatory transcription factor (IRF) family which regulates gene expression critical to immune response, hematopoiesis and proliferation. IRF-1 is a transcriptional activator for IFN-alpha, IFN-beta, and IFN-gamma stimulated genes. IRF1 is also a tumor suppressor transcription factor inducing apoptosis of tumorigenic cell lines. Recombinant human IRF1 was expressed in E.coli and purified by using conventional chromatography techniques.
Maruyama M.,et al.Nucleic Acids Res. 17:3292-3292(1989).
Miyamoto M.,et al.Cell 54:903-913(1988).
Cha Y.,et al.DNA Cell Biol. 11:605-611(1992).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Willman C.L.,et al.Science 259:968-971(1993).
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