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IRF1, human recombinant protein

Interferon regulatory factor-1, MAR

     
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Product info
Primary Accession P10914
Concentration 1
Calculated MW 15 kDa (134 aa, 1-114 aa + His tag), confirmed by MALDI-TOF.
Additional Info
Gene ID 3659
Gene Symbol IRF1
Other Names Interferon regulatory factor-1, MAR
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 N/A;
Recombinant Yes
Sequence MGSSHHHHHH SSGLVPRGSH MPITRMRMRP WLEMQINSNQ IPGLIWINKE EMIFQIPWKH AAKHGWDINK DACLFRSWAI HTGRYKAGEK EPDPKTWKAN FRCAMNSLPD IEEVKDQSRN KGSSAVRVYR MLPP
Target/Specificity IRF1
Format Liquid
Storage -80°C; 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) and 10% glycerol.
Citations (0)

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Background

IRF1, Interferon regulatory factor 1, is a member of the interferon regulatory transcription factor (IRF) family which regulates gene expression critical to immune response, hematopoiesis and proliferation. IRF-1 is a transcriptional activator for IFN-alpha, IFN-beta, and IFN-gamma stimulated genes. IRF1 is also a tumor suppressor transcription factor inducing apoptosis of tumorigenic cell lines. Recombinant human IRF1 was expressed in E.coli and purified by using conventional chromatography techniques.

References

Maruyama M.,et al.Nucleic Acids Res. 17:3292-3292(1989).
Miyamoto M.,et al.Cell 54:903-913(1988).
Cha Y.,et al.DNA Cell Biol. 11:605-611(1992).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Willman C.L.,et al.Science 259:968-971(1993).

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$ 295.00
Cat# PBV10945r
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