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IRF2, human recombinant protein

Interferon regulatory factor-2

     
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Product info
Primary Accession P14316
Concentration 1
Calculated MW 15 kDa (133 aa, 1-113 aa + His tag), confirmed by MALDI-TOF.
Additional Info
Gene ID 3660
Gene Symbol IRF2
Other Names Interferon regulatory factor-2
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant Yes
Sequence MGSSHHHHHH SSGLVPRGSH MPVERMRMRP WLEEQINSNT IPGLKWLNKE KKIFQIPWMH AARHGWDVEK DAPLFRNWAI HTGKHQPGVD KPDPKTWKAN FRCAMNSLPD IEEVKDKSIK KGNNAFRVYR MLP
Target/Specificity IRF2
Format Liquid
Storage -80°C; 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0), 1 mM DTT and 10% glycerol.
Citations (0)

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Background

Interferon regulatory factor (IRF) 2 is a member of the interferon regulatory transcription factor family. IRF-2 is generally regarded as an oncoprotein. Structure of IRF1 and IRF2 are similar. However, its functions are different. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. Recombinant human IRF2 was expressed in E.coli and purified by using conventional chromatography techniques.

References

Itoh S.,et al.Nucleic Acids Res. 17:8372-8372(1989).
Cha Y.,et al.J. Biol. Chem. 269:5279-5287(1994).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.

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$ 375.00
Cat# PBV10946r-100
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