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IL18, mouse recombinant protein

IL-18, IFN-gamma-inducing factor (IGIF), Interleukin-1 gamma

     
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Product info
Primary Accession P70380
Concentration 1
Calculated MW 20.4 kDa (178 aa, 36-192 aa + His Tag), confirmed by MALDI-TOF.
Additional Info
Gene ID 16173
Gene Symbol IL18
Other Names IL-18, IFN-gamma-inducing factor (IGIF), Interleukin-1 gamma
Gene Source Mouse
Source E. coli
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 N/A;
Recombinant Yes
Sequence MGSSHHHHHH SSGLVPRGSH MNFGRLHCTT AVIRNINDQV LFVDKRQPVF EDMTDIDQSA SEPQTRLIIY MYKDSEVRGL AVTLSVKDSK MSTLSCKNKI ISFEEMDPPE NIDDIQSDLI FFQKRVPGHN KMEFESSLYE GHFLACQKED DAFKLILKKK DENGDKSVMF TLTNLHQS
Target/Specificity IL18
Format Liquid
Storage -80°C; 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.
Citations (0)

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Background

Interleukin 18 (IL-18), previously known as interferon-gamma (IFN-gamma)-inducing factor, is an activator of NK cells and a co-inducer of Th1 cytokines. IL-18 is produced from Kupffer cells, activated macrophages, keratinocytes, intestinal epithelial cells, osteoblasts, adrenal cortex cells and murine diencephalon. IL-18 was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

References

Okamura H.,et al.Nature 378:88-91(1995).
Rothe H.,et al.J. Clin. Invest. 99:469-474(1997).

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$ 275.00
$ 475.00
Cat# PBV10950r-50
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