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SFTPD, human recombinant protein

Pulmonary surfactant-associated protein D precursor, COLEC7, PSP-D, SFTP4, SP-D

     
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Product info
Primary Accession P35247
Concentration 1
Calculated MW 18.9 kDa (175 aa, 224-375 aa + His Tag), confirmed by MALDI-TOF.
Additional Info
Gene ID 6441
Gene Symbol SFTPD
Other Names Pulmonary surfactant-associated protein D precursor, COLEC7, PSP-D, SFTP4, SP-D
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥80%
Assay2&Purity2 N/A;
Recombinant Yes
Sequence MGSSHHHHHH SSGLVPRGSH MGSVASLRQQ VEALQGQVQH LQAAFSQYKK VELFPNGQSV GEKIFKTAGF VKPFTEAQLL CTQAGGQLAS PRSAAENAAL QQLVVAKNEA AFLSMTDSKT EGKFTYPTGE SLVYSNWAPG EPNDDGGSED CVEIFTNGKW NDRACGEKRL VVCEF
Target/Specificity SFTPD
Format Liquid
Storage -80°C; 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, and 0.4 M Urea.
Citations (0)

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Background

SFTPD, as known as Surfactant pulmonary-associated protein D, is a member of the collectin family of C-type lectins that is synthesized in many tissues including respiratory epithelial cells in the lung, and contains one C-type lectin domain and one collagen-like domain. It is humoral molecules of the innate immune system, and is considered a functional candidate in chronic periodontitis. Besides it is involved in the development of acute and chronic inflammation of the lung. Several human lung diseases are characterized by decreased levels of bronchoalveolar SFTPD. Recombinant human SFTPD protein, fused to His-tag at N-terminus, was expressed in E.coli.

References

Lu J.,et al.Biochem. J. 284:795-802(1992).
Crouch E.,et al.J. Biol. Chem. 268:2976-2983(1993).
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Deloukas P.,et al.Nature 429:375-381(2004).
Crouch E.,et al.Am. J. Pathol. 142:241-248(1993).

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$ 295.00
Cat# PBV10952r
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