SLAMF6, human recombinant protein
SLAM family member 6, CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000
|Calculated MW||25.5 kDa (228 aa, 22-226 aa + His Tag), confirmed by MALDI-TOF.|
|Other Names||SLAM family member 6, CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000|
|Sequence||MGSSHHHHHH SSGLVPRGSH MGSQSSLTPL MVNGILGESV TLPLEFPAGE KVNFITWLFN ETSLAFIVPH ETKSPEIHVT NPKQGKRLNF TQSYSLQLSN LKMEDTGSYR AQISTKTSAK LSSYTLRILR QLRNIQVTNH SQLFQNMTCE LHLTCSVEDA DDNVSFRWEA LGNTLSSQPN LTVSWDPRIS SEQDYTCIAE NAVSNLSFSV SAQKLCEDVK IQYTDTKM|
|Storage||-80°C; 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, and 0.4 M Urea.|
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Provided below are standard protocols that you may find useful for product applications.
SLAM family member 6, also known as SLAMF6, belongs to the SLAM family of immune cell receptors. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. SLAMF6 is expressed on NK-, T-, and B cells. It exhibits homotypic interactions and can associate with adaptor molecules such as SAP to modulate immune cell functions. Recombinant human SLAMF6 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Bottino C.,et al.J. Exp. Med. 194:235-246(2001).
Bottino C.,et al.J. Exp. Med. 194:705-705(2001).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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