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OSTF1, human recombinant protein

Osteoclast stimulating factor 1, SH3P2, OSF

     
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Product info
Primary Accession Q92882
Concentration 1
Calculated MW 25.1 kDa (225 aa, 1-217 aa + His Tag), confirmed by MALDI-TOF. (MW on SDS-PAGE shifts up)
Additional Info
Gene ID 26578
Gene Symbol OSTF1
Other Names Osteoclast stimulating factor 1, SH3P2, OSF
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant Yes
Sequence MSKPPPKPVK PGEGGQVKVF RALYTFEPRT PDELYFEEGD IIYITDMSDT NWWKGTSKGR TGLIPSNYVA EQAESIDNPL HEAAKRGNLS WLRECLDNRV GVNGLDKAGS TALYWACHGG HKDIVEMLFT QPNIELNQQN KLGDTALHAA AWKGYADIVQ LFLAKGARTD LRNIEKKLAF DMATNAACAS LLKKKQGTDA VRTLSNAEDY LDDEDSDLEH HHHHH
Target/Specificity OSTF1
Format Liquid
Storage -80°C; 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, and 0.5 mM DTT.
Citations (0)

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Background

Osteoclast-stimulating factor-1 (OSTF1) is an intracellular protein produced by osteoclasts that indirectly induces osteoclast (OCL) formation and bone resorption. OSTF1 is highly expressed in OCL and contains structural domains such as SH3 and ankyrin repeats, which are potentially involved in protein-protein interactions. OSTF1 is ubiquitously expressed analogous to other regulators of OCL activity such as c-Src or transforming growth factor beta. Recombinant human OSTF1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

References

Reddy S.V.,et al.J. Cell. Physiol. 177:636-645(1998).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Humphray S.J.,et al.Nature 429:369-374(2004).
Roodman G.D.,et al.Unpublished observations (NOV-2000).
Kurihara N.,et al.J. Biol. Chem. 276:41035-41039(2001).

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$ 225.00
Cat# PBV10960r
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