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CCL21, human recombinant protein
C-C motif chemokine 21, 6Ckine, CKb9, ECL, SCYA21, SLC, TCA4.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O00585 |
|---|---|
| Concentration | 0.5 |
| Calculated MW | 14.5 kDa (132 aa, 24-134 aa + His Tag), confirmed by MALDI-TOF. |
| Gene ID | 6366 |
|---|---|
| Gene Symbol | CCL21 |
| Other Names | C-C motif chemokine 21, 6Ckine, CKb9, ECL, SCYA21, SLC, TCA4. |
| Gene Source | Human |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥90% |
| Assay2&Purity2 | N/A; |
| Recombinant | Yes |
| Sequence | MGSSHHHHHH SSGLVPRGSH MSDGGAQDCC LKYSQRKIPA KVVRSYRKQE PSLGCSIPAI LFLPRKRSQA ELCADPKELW VQQLMQHLDK TPSPQKPAQG CRKDRGASKT GKKGKGSKGC KRTERSQTPK GP |
| Target/Specificity | CCL21 |
| Format | Liquid |
| Storage | -80°C; 0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, and 1 mM DTT. |
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Provided below are standard protocols that you may find useful for product applications.
Background
CCL21 is member of the chemokine superfamily and the subfamily of CC chemokines that has an aspartate cysteine-cysteine-leucine motif near its amino-terminus. This protein is involved in inhibits hemopoiesis and stimulates chemotaxis. CCL21 is chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. It may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. Recombinant CCL21 protein was expressed in E.coli and purified by using conventional chromatography techniques.
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