|Calculated MW||14.5 kDa (132 aa, 24-134 aa + His Tag), confirmed by MALDI-TOF.|
|Other Names||C-C motif chemokine 21, 6Ckine, CKb9, ECL, SCYA21, SLC, TCA4.|
|Sequence||MGSSHHHHHH SSGLVPRGSH MSDGGAQDCC LKYSQRKIPA KVVRSYRKQE PSLGCSIPAI LFLPRKRSQA ELCADPKELW VQQLMQHLDK TPSPQKPAQG CRKDRGASKT GKKGKGSKGC KRTERSQTPK GP|
|Storage||-80°C; 0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, and 1 mM DTT.|
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CCL21 is member of the chemokine superfamily and the subfamily of CC chemokines that has an aspartate cysteine-cysteine-leucine motif near its amino-terminus. This protein is involved in inhibits hemopoiesis and stimulates chemotaxis. CCL21 is chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. It may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. Recombinant CCL21 protein was expressed in E.coli and purified by using conventional chromatography techniques.
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