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CD244, human recombinant protein

CD244 molecule, natural killer cell receptor 2B4, 2B4, NAIL, NKR2B4, Nmrk, SLAMF4

     
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Product info
Primary Accession Q9BZW8
Concentration 0.5
Calculated MW 25.5 kDa (230 aa, 19-224 aa + His Tag), confirmed by MALDI-TOF.
Additional Info
Gene ID 51744
Gene Symbol CD244
Other Names CD244 molecule, natural killer cell receptor 2B4, 2B4, NAIL, NKR2B4, Nmrk, SLAMF4
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥85%
Assay2&Purity2 N/A;
Recombinant Yes
Sequence MGSSHHHHHH SSGLVPRGSH MGSH GKGCQG SADHVVSISG VPLQLQPNSI QTKVDSIAWK KLLPSQNGFH HILKWENGSL PSNTSNDRFS FIVKNLSLLI KAAQQQDSGL YCLEVTSISG KVQTATFQVF VFDKVEKPRL QGQGKILDRG RCQVALSCLV SRDGNVSYAW YRGSKLIQTA GNLTYLDEEV DINGTHTYTC NVSNPVSWES HTLNLTQDCQ NAHQEFRFWP
Target/Specificity CD244
Format Liquid
Storage -80°C; 0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea.
Citations (0)

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Background

CD244 (Natural Killer Cell Receptor 2B4), also known as Cluster of Differentiation 244, contains 2 Ig-like (immunoglobulin-like) domains. A role for the subtypes of CD2 Ig superfamily receptors has been recently demonstrated in eosinophilic inflammation in experimental asthma and atopic asthmatics. Functions of CD244 molecules are in eosinophil adhesion and chemotaxis, and correlated the results to the pathophysiology of allergic rhinitis (AR). The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Recombinant human CD244 protein, fused to His-tag at N-terminus, was expressed in E.coli.

References

Nakajima H.,et al.Eur. J. Immunol. 29:1676-1683(1999).
Kubin M.Z.,et al.Eur. J. Immunol. 29:3466-3477(1999).
Tangye S.G.,et al.J. Immunol. 162:6981-6985(1999).
Boles K.S.,et al.Tissue Antigens 54:27-34(1999).
Kumaresan P.R.,et al.Immunogenetics 51:987-992(2000).

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$ 295.00
Cat# PBV10963r-50
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