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IL13RA2, human recombinant protein
Interleukin-13 receptor subunit alpha-2 precursor, CD213A2, CT19, IL-13R, IL13BP
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q14627 |
|---|---|
| Concentration | 1 |
| Calculated MW | 39.5 kDa (340 aa, 27-343 aa + His Tag), confirmed by MALDI-TOF. |
| Gene ID | 3598 |
|---|---|
| Gene Symbol | IL13RA2 |
| Other Names | Interleukin-13 receptor subunit alpha-2 precursor, CD213A2, CT19, IL-13R, IL13BP |
| Gene Source | Human |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥85% |
| Assay2&Purity2 | N/A; |
| Recombinant | Yes |
| Sequence | MGSSHHHHHH SSGLVPRGSH MGSDTEIKVN PPQDFEIVDP GYLGYLYLQW QPPLSLDHFK ECTVEYELKY RNIGSETWKT IITKNLHYKD GFDLNKGIEA KIHTLLPWQC TNGSEVQSSW AETTYWISPQ GIPETKVQDM DCVYYNWQYL LCSWKPGIGV LLDTNYNLFY WYEGLDHALQ CVDYIKADGQ NIGCRFPYLE ASDYKDFYIC VNGSSENKPI RSSYFTFQLQ NIVKPLPPVY LTFTRESSCE IKLKWSIPLG PIPARCFDYE IEIREDDTTL VTATVENETY TLKTTNETRQ LCFVVRSKVN IYCSDDGIWS EWSDKQCWEG EDLSKKTLLR |
| Target/Specificity | IL13RA2 |
| Format | Liquid |
| Storage | -80°C; 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol. |
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Provided below are standard protocols that you may find useful for product applications.
Background
IL13RA2 is closely related to Il13RA1, a subunit of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. Recombinant human IL13RA2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
References
Caput D.,et al.J. Biol. Chem. 271:16921-16926(1996).
Donaldson D.D.,et al.Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases.
Guo J.,et al.Genomics 42:141-145(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ross M.T.,et al.Nature 434:325-337(2005).
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