|Calculated MW||19 kDa (171 aa, 94-240 aa + His Tag), confirmed by MALDI-TOF.|
|Other Names||Killer cell lectin-like receptor subfamily C, NKG2-E; NKG2E|
|Sequence||MGSSHHHHHH SSGLVPRGSH MGSM IPFLEQ NNSSPNTRTQ KARPCGHCPE EWITYSNSCY YIGKERRTWE ESLQACASKN SSSLLSIDNE EEMKFLASIL PSSWIGVFRN SSHHPWVTIN GLAFKHEIKD SDHAERNCAM LHVRGLISDQ CGSSRIIRRG FIMLTRLVLN S|
|Storage||-80°C; 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M NaCl and 10% glycerol.|
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Provided below are standard protocols that you may find useful for product applications.
KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Recombinant human KLRC3 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Adamkiewicz T.V.,et al.Immunogenetics 39:218-218(1994).
Glienke J.,et al.Immunogenetics 48:163-173(1998).
Bellon T.,et al.J. Immunol. 162:3996-4002(1999).
Shum B.P.,et al.J. Immunol. 168:240-252(2002).
Kothapalli R.,et al.Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.
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