Galectin-4, human recombinant protein
LGALS4, GAL4, L36LBP, Lactose-binding lectin 4.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P56470 |
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Concentration | 1 |
Calculated MW | 38.1 kDa (343 aa, 1-323 aa + His Tag). |
Gene ID | 3960 |
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Gene Symbol | LGALS4 |
Other Names | LGALS4, GAL4, L36LBP, Lactose-binding lectin 4. |
Gene Source | Human |
Source | E. coli |
Assay&Purity | SDS-PAGE; ≥95% |
Assay2&Purity2 | N/A; |
Recombinant | Yes |
Sequence | MGSSHHHHHH SSGLVPRGSH MAYVPAPGYQ PTYNPTLPYY QPIPGGLNVG MSVYIQGVAS EHMKRFFVNF VVGQDPGSDV AFHFNPRFDG WDKVVFNTLQ GGKWGSEERK RSMPFKKGAA FELVFIVLAE HYKVVVNGNP FYEYGHRLPL QMVTHLQVDG DLQLQSINFI GGQPLRPQGP PMMPPYPGPG HCHQQLNSLP TMEGPPTFNP PVPYFGRLQG GLTARRTIII KGYVPPTGKS FAINFKVGSS GDIALHINPR MGNGTVVRNS LLNGSWGSEE KKITHNPFGP GQFFDLSIRC GLDRFKVYAN GQHLFDFAHR LSAFQRVDTL EIQGDVTLSY VQI |
Target/Specificity | Galectin-4 |
Format | Liquid |
Storage | -80°C; 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT and 10% glycerol. |
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Background
Galectin-4 belongs to a subfamily of galectins composed of two carbohydrate recognition domains within the same peptide chain. The galectins are a family of beta-galactosidase-binding proteins implicated in modulating cell-cell and cell-matrix interactions, which inhibits chronic inflammations, GVHD, and allergic reactions. The expression of this gene is restricted to small intestine, colon, and rectum, and it is under expressed in colorectal cancer. Recombinant Galectin-4 protein was expressed in E.coli and purified by using conventional chromatography techniques.
References
Kato S.,et al.Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases.
Rechreche H.,et al.Eur. J. Biochem. 248:225-230(1997).
Huflejt M.E.,et al.J. Biol. Chem. 272:14294-14303(1997).
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