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Galectin-4, human recombinant protein

LGALS4, GAL4, L36LBP, Lactose-binding lectin 4.

     
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Product info
Primary Accession P56470
Concentration 1
Calculated MW 38.1 kDa (343 aa, 1-323 aa + His Tag).
Additional Info
Gene ID 3960
Gene Symbol LGALS4
Other Names LGALS4, GAL4, L36LBP, Lactose-binding lectin 4.
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant Yes
Sequence MGSSHHHHHH SSGLVPRGSH MAYVPAPGYQ PTYNPTLPYY QPIPGGLNVG MSVYIQGVAS EHMKRFFVNF VVGQDPGSDV AFHFNPRFDG WDKVVFNTLQ GGKWGSEERK RSMPFKKGAA FELVFIVLAE HYKVVVNGNP FYEYGHRLPL QMVTHLQVDG DLQLQSINFI GGQPLRPQGP PMMPPYPGPG HCHQQLNSLP TMEGPPTFNP PVPYFGRLQG GLTARRTIII KGYVPPTGKS FAINFKVGSS GDIALHINPR MGNGTVVRNS LLNGSWGSEE KKITHNPFGP GQFFDLSIRC GLDRFKVYAN GQHLFDFAHR LSAFQRVDTL EIQGDVTLSY VQI
Target/Specificity Galectin-4
Format Liquid
Storage -80°C; 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT and 10% glycerol.
Citations (0)
citation

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Background

Galectin-4 belongs to a subfamily of galectins composed of two carbohydrate recognition domains within the same peptide chain. The galectins are a family of beta-galactosidase-binding proteins implicated in modulating cell-cell and cell-matrix interactions, which inhibits chronic inflammations, GVHD, and allergic reactions. The expression of this gene is restricted to small intestine, colon, and rectum, and it is under expressed in colorectal cancer. Recombinant Galectin-4 protein was expressed in E.coli and purified by using conventional chromatography techniques.

References

Kato S.,et al.Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases.
Rechreche H.,et al.Eur. J. Biochem. 248:225-230(1997).
Huflejt M.E.,et al.J. Biol. Chem. 272:14294-14303(1997).

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Discontinued
Cat# PBV10987r-100
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