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Galectin-9, human recombinant protein
LGALS9, Gal-9, Tumor antigen HOM-HD-21, Ecalectin.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O00182 |
|---|---|
| Concentration | 0.5 |
| Calculated MW | 18.5 kDa (168 aa, 1-148 aa + His Tag). |
| Gene ID | 3965 |
|---|---|
| Gene Symbol | LGALS9 |
| Other Names | LGALS9, Gal-9, Tumor antigen HOM-HD-21, Ecalectin. |
| Gene Source | Human |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥90% |
| Assay2&Purity2 | N/A; |
| Recombinant | Yes |
| Sequence | MGSSHHHHHH SSGLVPRGSH MAFSGSQAPY LSPAVPFSGT IQGGLQDGLQ ITVNGTVLSS SGTRFAVNFQ TGFSGNDIAF HFNPRFEDGG YVVCNTRQNG SWGPEERKTH MPFQKGMPFD LCFLVQSSDF KVMVNGILFV QYFHRVPFHR VDTISVNGSV QLSYISFQ |
| Target/Specificity | Galectin-9 |
| Format | Liquid |
| Storage | -80°C; 0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM NaCl and 20% glycerol. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Galectin-9 (Gal-9) is a member of animal lectins that have an affinity to beta-galactosides and Forssman pentasaccharide. It is strongly overexpressed in Hodgkin's disease tissue and it might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its consistently associated immunodeficiency. Recombinant Galectin-9 protein was expressed in E.coli and purified by using conventional chromatography techniques.
References
Tuereci O.,et al.J. Biol. Chem. 272:6416-6422(1997).
Kato S.,et al.Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases.
Matsumoto R.,et al.J. Biol. Chem. 273:16976-16984(1998).
Nakajima H.,et al.Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases.
Akiyama S.,et al.Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
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