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Human CellExp CD47, human recombinant protein

CD47, MER6, IAP, OA3

Product info
Primary Accession Q08722
Calculated MW This protein is fused with 6×His tag at the C-terminus, has a calculated MW of 14.5 kDa. The predicted N-terminus is Gln 19. DTT-reduced Protein migrates as 35-43 kDa due to glycosylation.
Additional Info
Gene ID 961
Gene Symbol CD47
Other Names CD47, MER6, IAP, OA3
Gene Source Human
Source HEK293 cells
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant Yes
Results Measured by its binding ability in a functional ELISA. When Recombinant Human CD172a / SIRP alpha Fc Chimera is coated at 1 µg/mL, rhCD47 binds with apparent Kd < 1 nM.
Target/Specificity CD47
Application Notes Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
Format Lyophilized
Storage -20°C; Lyophilized from 0.22 µm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.
Citations (0)

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Leukocyte surface antigen CD47 also known as antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances super antigen-dependent T-cell-mediated proliferation and co-stimulates T-cell activation.


Campbell I.G.,et al.Cancer Res. 52:5416-5420(1992).
Lindberg F.P.,et al.J. Cell Biol. 123:485-496(1993).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 195.00
Cat# PBV11008r
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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